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iloperidone will increase amounts of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Iloperidone is really a time-dependent CYP3A inhibitor and could result in greater plasma levels of drugs predominantly eradicated by CYP3A4.Xiao et al (2004) applied publish mortem examination with the brains of MPTP addresse